The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09

Objectives. HLA-B*27:05 is associated with AS whereas HLA-B*27:09 is not associated. We hypothesized that different interactions with KIR immune receptors could contribute to the difference in disease association between HLA-B*27:05 and HLAB*27:09. Thus, the objective of this study was to compare th...

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Autori principali: Cauli, Alberto, Shaw, Jacqueline, Giles, Joanna, Hatano, Hiroko, Rysnik, Oliwia, Payeli, Sravan, McHugh, Kirsty, Dessole, Grazia, Porru, Giovanni, Desogus, Elisabetta, Fiedler, Sarah, Hölper, Soraya, Carette, Amanda, Blanco-Gelaz, Miguel Angel, Vacca, Alessandra, Piga, Matteo, Ibba, Valentina, Garau, Pietro, La Nasa, Giorgio, López-Larrea, Carlos, Mathieu, Alessandro, Renner, Christoph, Bowness, Paul, Kollnberger, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798713/
https://ncbi.nlm.nih.gov/pubmed/23804219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ket219
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