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Loss of CCR5 results in glucose intolerance in diet-induced obese mice

Macrophage and T cell infiltration into metabolic tissues contributes to obesity-associated inflammation and insulin resistance (IR). C-C chemokine receptor 5 (CCR5), expressed on macrophages and T cells, plays a critical role in the recruitment and activation of proinflammatory M1 and T(H)1 immune...

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Main Authors: Kennedy, Arion, Webb, Corey D., Hill, Andrea A., Gruen, Marnie L., Jackson, Laurel G., Hasty, Alyssa H.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798705/
https://ncbi.nlm.nih.gov/pubmed/23941876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00177.2013
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