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Regulation of large-conductance Ca(2+)-activated K(+) channels by WNK4 kinase

Large-conductance, Ca(2+)-activated K(+) channels, commonly referred to as BK channels, have a major role in flow-induced K(+) secretion in the distal nephron. With-no-lysine kinase 4 (WNK4) is a serine-threonine kinase expressed in the distal nephron that inhibits ROMK activity and renal K(+) secre...

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Autors principals: Wang, Zhijian, Subramanya, Arohan R., Satlin, Lisa M., Pastor-Soler, Núria M., Carattino, Marcelo D., Kleyman, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798677/
https://ncbi.nlm.nih.gov/pubmed/23885063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00133.2013
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