FoxO1 Deacetylation Regulates Thyroid Hormone-induced Transcription of Key Hepatic Gluconeogenic Genes

Hepatic gluconeogenesis is a concerted process that integrates transcriptional regulation with hormonal signals. A major regulator is thyroid hormone (TH), which acts through its nuclear receptor (TR) to induce the expression of the hepatic gluconeogenic genes, phosphoenolpyruvate carboxykinase (PCK...

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Bibliografiska uppgifter
Huvudupphovsmän: Singh, Brijesh Kumar, Sinha, Rohit Anthony, Zhou, Jin, Xie, Sherwin Ying, You, Seo-Hee, Gauthier, Karine, Yen, Paul Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Gene Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798501/
https://ncbi.nlm.nih.gov/pubmed/23995837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504845
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