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Human TEN1 Maintains Telomere Integrity and Functions in Genome-wide Replication Restart

TEN1 is a component of the mammalian CTC1-STN1-TEN1 complex. CTC1 and/or STN1 functions in telomere duplex replication, C-strand fill-in, and genome-wide restart of replication following fork stalling. Here we examine the role of human TEN1 and ask whether it also functions as a specialized replicat...

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Autori principali: Kasbek, Christopher, Wang, Feng, Price, Carolyn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798482/
https://ncbi.nlm.nih.gov/pubmed/24025336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493478
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