The m Subunit of Murine Translation Initiation Factor eIF3 Maintains the Integrity of the eIF3 Complex and Is Required for Embryonic Development, Homeostasis, and Organ Size Control

Mammalian eIF3 is composed of 13 subunits and is the largest eukaryotic initiation factor. eIF3 plays a key role in protein biosynthesis. However, it is not fully understood how different subunits contribute to the structural integrity and function of the eIF3 complex. Whether eIF3 is essential for...

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Autores principales: Zeng, Liyong, Wan, Yihan, Li, Dan, Wu, Jing, Shao, Mengle, Chen, Jiong, Hui, Lijian, Ji, Hongbin, Zhu, Xueliang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798477/
https://ncbi.nlm.nih.gov/pubmed/24003236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.506147
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