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Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity

PURPOSE: The combination of a platinum and taxane are standard of care for many cancers, but the utility is often limited due to debilitating neurotoxicity. We examined whether single nucleotide polymorphisms (SNPs) from annotated candidate genes will identify genetic risk for chemotherapy-induced n...

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Detalhes bibliográficos
Main Authors: McWhinney-Glass, Sarah, Winham, Stacey J., Hertz, Daniel L., Revollo, Jane Yen, Paul, Jim, He, Yijing, Brown, Robert, Motsinger-Reif, Alison A., McLeod, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798385/
https://ncbi.nlm.nih.gov/pubmed/23963862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0774
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