A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression

The U1 small nuclear ribonucleoprotein (snRNP)-specific U1C protein participates in 5′ splice site recognition and regulation of pre-mRNA splicing. Based on an RNA-Seq analysis in HeLa cells after U1C knockdown, we found a conserved, intra-U1 snRNP cross-regulation that links U1C and U1-70K expressi...

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Main Authors: Rösel-Hillgärtner, Tanja Dorothe, Hung, Lee-Hsueh, Khrameeva, Ekaterina, Le Querrec, Patrick, Gelfand, Mikhail S., Bindereif, Albrecht
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798272/
https://ncbi.nlm.nih.gov/pubmed/24146627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003856
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