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Direct Induction of Chondrogenic Cells from Human Dermal Fibroblast Culture by Defined Factors

The repair of large cartilage defects with hyaline cartilage continues to be a challenging clinical issue. We recently reported that the forced expression of two reprogramming factors (c-Myc and Klf4) and one chondrogenic factor (SOX9) can induce chondrogenic cells from mouse dermal fibroblast cultu...

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Detalhes bibliográficos
Main Authors: Outani, Hidetatsu, Okada, Minoru, Yamashita, Akihiro, Nakagawa, Kanako, Yoshikawa, Hideki, Tsumaki, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797820/
https://ncbi.nlm.nih.gov/pubmed/24146984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077365
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