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Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors

Repair of cartilage injury with hyaline cartilage continues to be a challenging clinical problem. Because of the limited number of chondrocytes in vivo, coupled with in vitro de-differentiation of chondrocytes into fibrochondrocytes, which secrete type I collagen and have an altered matrix architect...

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Detalhes bibliográficos
Main Authors: Hiramatsu, Kunihiko, Sasagawa, Satoru, Outani, Hidetatsu, Nakagawa, Kanako, Yoshikawa, Hideki, Tsumaki, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026734/
https://ncbi.nlm.nih.gov/pubmed/21293062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44605
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