Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein

Entry of HIV-1 into target cells requires binding of the viral envelope glycoprotein (Env) to cellular receptors and subsequent conformational changes that culminates in fusion of viral and target cell membranes. Recent structural information has revealed that these conformational transitions are re...

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書誌詳細
主要な著者: Kassa, Aemro, Dey, Antu K., Sarkar, Pampi, Labranche, Celia, Go, Eden P., Clark, Daniel F., Sun, Yide, Nandi, Avishek, Hartog, Karin, Desaire, Heather, Montefiori, David, Carfi, Andrea, Srivastava, Indresh K., Barnett, Susan W.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797752/
https://ncbi.nlm.nih.gov/pubmed/24146829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076139
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