Positive Selection in Bone Morphogenetic Protein 15 Targets a Natural Mutation Associated with Primary Ovarian Insufficiency in Human

Bone Morphogenetic Protein 15 (BMP15) is a TGFβ-like oocyte-derived growth factor involved in ovarian folliculogenesis as a critical regulator of many granulosa cell processes. Alterations of the BMP15 gene have been found associated with different ovarian phenotypic effects depending on the species...

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Bibliographic Details
Main Authors: Auclair, Sylvain, Rossetti, Raffaella, Meslin, Camille, Monestier, Olivier, Di Pasquale, Elisa, Pascal, Géraldine, Persani, Luca, Fabre, Stéphane
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797742/
https://ncbi.nlm.nih.gov/pubmed/24147118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078199
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