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Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation

OBJECTIVES: There is no pharmacokinetic interaction between tenofovir and nevirapine, but a higher emergence rate of resistance mutations has been reported when these drugs are coadministered. We sought to examine if there is a potential intracellular interaction that may account for the emergence o...

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Autors principals: Liptrott, N. J., Curley, P., Moss, D., Back, D. J., Khoo, S. H., Owen, A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797642/
https://ncbi.nlm.nih.gov/pubmed/23794601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt225
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