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Tyrosine Kinase Signal Modulation: A Matter of H(2)O(2) Membrane Permeability?
H(2)O(2) produced by extracellular NADPH oxidases regulates tyrosine kinase signaling inhibiting phosphatases. How does it cross the membrane to reach its cytosolic targets? Silencing aquaporin-8 (AQP8), but not AQP3 or AQP4, inhibited H(2)O(2) entry into HeLa cells. Re-expression of AQP8 with silen...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797449/ https://ncbi.nlm.nih.gov/pubmed/23541115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5330 |
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