Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo

BACKGROUND: Minnelide, a pro-drug of triptolide, has recently emerged as a potent anticancer agent. The precise mechanisms of its cytotoxic effects remain unclear. METHODS: Cell viability was studied using CCK8 assay. Cell proliferation was measured real-time on cultured cells using Electric Cell Su...

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Bibliographic Details
Main Authors: Rousalova, Ilona, Banerjee, Sulagna, Sangwan, Veena, Evenson, Kristen, McCauley, Joel A., Kratzke, Robert, Vickers, Selwyn M., Saluja, Ashok, D’Cunha, Jonathan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797124/
https://ncbi.nlm.nih.gov/pubmed/24143232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077411
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