NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium

Infections, microbe sampling and occasional leakage of commensal microbiota and their products across the intestinal epithelial cell layer represent a permanent challenge to the intestinal immune system. The production of reactive oxygen species by NADPH oxidase is thought to be a key element of def...

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Main Authors: Felmy, Boas, Songhet, Pascal, Slack, Emma Marie Caroline, Müller, Andreas J., Kremer, Marcus, Van Maele, Laurye, Cayet, Delphine, Heikenwalder, Mathias, Sirard, Jean-Claude, Hardt, Wolf-Dietrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797104/
https://ncbi.nlm.nih.gov/pubmed/24143212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077204
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