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TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127(+) immune cells in spleen and mucosa
In adaptive immunity, T helper-17 lymphocytes produce the IL-17 and IL-22 cytokines that stimulate mucosal antimicrobial defenses and tissue repair. Here, we observed that the TLR5 agonist flagellin induced swift and transient transcription genes encoding IL-17 and IL-22 in lymphoid, gut and lung ti...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association of Immunologists
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060348/ https://ncbi.nlm.nih.gov/pubmed/20566828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000115 |
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