TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127(+) immune cells in spleen and mucosa

In adaptive immunity, T helper-17 lymphocytes produce the IL-17 and IL-22 cytokines that stimulate mucosal antimicrobial defenses and tissue repair. Here, we observed that the TLR5 agonist flagellin induced swift and transient transcription genes encoding IL-17 and IL-22 in lymphoid, gut and lung ti...

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Bibliografski detalji
Glavni autori: Van Maele, Laurye, Carnoy, Christophe, Cayet, Delphine, Songhet, Pascal, Dumoutier, Laure, Ferrero, Isabel, Janot, Laure, Erard, François, Bertout, Julie, Leger, Hélène, Sebbane, Florent, Benecke, Arndt, Renauld, Jean-Christophe, Hardt, Wolf-Dietrich, Ryffel, Bernhard, Sirard, Jean-Claude
Format: Artigo
Jezik:Inglês
Izdano: American Association of Immunologists 2010
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060348/
https://ncbi.nlm.nih.gov/pubmed/20566828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000115
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