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MADM-ML, a Mouse Genetic Mosaic System with Increased Clonal Efficiency

Mosaic Analysis with Double Markers (MADM) is a mouse genetic system that allows simultaneous gene knockout and fluorescent labeling of sparse, clonally-related cells within an otherwise normal mouse, thereby circumventing embryonic lethality problems and providing single-cell resolution for phenoty...

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Autori principali: Henner, Astra, Ventura, P. Britten, Jiang, Ying, Zong, Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797059/
https://ncbi.nlm.nih.gov/pubmed/24143253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077672
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