Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans

Current yearly influenza virus vaccines induce strain-specific neutralizing antibody (NAb) responses providing protective immunity to closely matched viruses. However, these vaccines are often poorly effective in high-risk groups such as the elderly and challenges exist in predicting yearly or emerg...

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Detalhes bibliográficos
Main Authors: Dolfi, Douglas V., Mansfield, Kathleen D., Kurupati, Raj K., Kannan, Senthil, Doyle, Susan A., Ertl, Hildegund C. J., Schmader, Kenneth E., Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796569/
https://ncbi.nlm.nih.gov/pubmed/24155927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077164
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