Improved PCR Performance Using Template DNA from Formalin-Fixed and Paraffin-Embedded Tissues by Overcoming PCR Inhibition

Formalin-fixed and paraffin-embedded (FFPE) tissues represent a valuable source for biomarker studies and clinical routine diagnostics. However, they suffer from degradation of nucleic acids due to the fixation process. Since genetic and epigenetic studies usually require PCR amplification, this deg...

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מידע ביבליוגרפי
Main Authors: Dietrich, Dimo, Uhl, Barbara, Sailer, Verena, Holmes, Emily Eva, Jung, Maria, Meller, Sebastian, Kristiansen, Glen
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796491/
https://ncbi.nlm.nih.gov/pubmed/24155973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077771
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