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Regulation of hepatitis B virus replication by epigenetic mechanisms and microRNAs
The hepatitis B virus (HBV) genome forms a covalently closed circular DNA (cccDNA) minichromosome that persists in the nucleus of virus-infected hepatocytes. HBV cccDNA serves as the template for viral mRNA synthesis and is subject to epigenetic regulation by several mechanisms, including DNA methyl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3796260/ https://ncbi.nlm.nih.gov/pubmed/24133502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00202 |
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