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Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory

Impaired memory may result from synaptic glutamatergic dysregulation related to chronic neuroinflammation. GLT1 is the primary excitatory amino acid transporter responsible for regulating extracellular glutamate levels in the hippocampus. We tested the hypothesis that if impaired spatial memory resu...

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Detalhes bibliográficos
Main Authors: Brothers, Holly M., Bardou, Isabelle, Hopp, Sarah C., Kaercher, Roxanne M., Corona, Angela W., Fenn, Ashley M., Godbout, Jonathan P., Wenk, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795939/
https://ncbi.nlm.nih.gov/pubmed/23709339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-013-9476-2
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