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Honokiol mediated inhibition of PI3K/mTOR pathway: A potential strategy to overcome immunoresistance in glioma, breast and prostate carcinoma without impacting T cell function
Inhibition of the PI3K/mTOR pathway is an appealing method for decreasing immunoresistance and augmenting T cell mediated immunotherapy. A major impediment to this strategy is the impact of conventional PI3K/mTOR pathway inhibitors on T cell function. In particular, Rapamycin, a well known immunosup...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795513/ https://ncbi.nlm.nih.gov/pubmed/19483651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181a8efe6 |
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