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Crystal structure of the Alpha subunit PAS domain from soluble guanylyl cyclase
Soluble guanylate cyclase (sGC) is a heterodimeric heme protein of ∼150 kDa and the primary nitric oxide receptor. Binding of NO stimulates cyclase activity, leading to regulation of cardiovascular physiology and providing attractive opportunities for drug discovery. How sGC is stimulated and where...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795502/ https://ncbi.nlm.nih.gov/pubmed/23934793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2331 |
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