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Inactivating mutation in histone deacetylase 3 stabilizes its active conformation
Histone deacetylases (HDACs), together with histone acetyltransferases (HATs), regulate gene expression by modulating the acetylation level of chromatin. HDAC3 is implicated in many important cellular processes, particularly in cancer cell proliferation and metastasis, making inhibition of HDAC3 a p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795489/ https://ncbi.nlm.nih.gov/pubmed/23904210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2317 |
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