Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon

Altered microRNA (miRNA) expression is frequently observed in acute myelogenous leukemia (AML) and has been implicated in leukemic transformation. Whether somatic copy number alterations (CNAs) are a frequent cause of altered miRNA gene expression is largely unknown. Herein, we used comparative geno...

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Autors principals: Ramsingh, Giridharan, Jacoby, Meagan A., Shao, Jin, De Jesus Pizzaro, Rigoberto E., Shen, Dong, Trissal, Maria, Getz, Angela H., Ley, Timothy J., Walter, Matthew J., Link, Daniel C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795465/
https://ncbi.nlm.nih.gov/pubmed/24009227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-488007
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