Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon

Altered microRNA (miRNA) expression is frequently observed in acute myelogenous leukemia (AML) and has been implicated in leukemic transformation. Whether somatic copy number alterations (CNAs) are a frequent cause of altered miRNA gene expression is largely unknown. Herein, we used comparative geno...

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Detalhes bibliográficos
Main Authors: Ramsingh, Giridharan, Jacoby, Meagan A., Shao, Jin, De Jesus Pizzaro, Rigoberto E., Shen, Dong, Trissal, Maria, Getz, Angela H., Ley, Timothy J., Walter, Matthew J., Link, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795465/
https://ncbi.nlm.nih.gov/pubmed/24009227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-488007
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