Role of Hydroxamate-Based Histone Deacetylase Inhibitors (Hb-HDACIs) in the Treatment of Solid Malignancies

Hydroxamate-based histone deacetylase inhibitors (Hb-HDACIs), such as vorinostat, belinostat and panobinostat, have been previously shown to have a wide range of activity in hematologic malignancies such as cutaneous T-cell lymphoma and multiple myeloma. Recent data show that they synergize with a v...

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Main Authors: Grassadonia, Antonino, Cioffi, Pasquale, Simiele, Felice, Iezzi, Laura, Zilli, Marinella, Natoli, Clara
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2013
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795372/
https://ncbi.nlm.nih.gov/pubmed/24202327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5030919
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