Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells

Invadopodia-dependent degradation of the basement membrane plays a major role during metastasis of breast cancer cells. Basement membrane degradation is mediated by targeted secretion of various matrix metalloproteinases (MMPs). Specifically, MMP2 and MMP9 (MMP2/9) possess the ability to hydrolyze c...

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Dades bibliogràfiques
Autors principals: Jacob, Abitha, Jing, Jian, Lee, James, Schedin, Pepper, Gilbert, Simon M., Peden, Andrew A., Junutula, Jagath R., Prekeris, Rytis
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795337/
https://ncbi.nlm.nih.gov/pubmed/23902685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.126573
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