Physicochemical Factors Controlling the Activity and Energy Coupling of an Ionic Strength-gated ATP-binding Cassette (ABC) Transporter

Cells control their volume through the accumulation of compatible solutes. The bacterial ATP-binding cassette transporter OpuA couples compatible solute uptake to ATP hydrolysis. Here, we study the gating mechanism and energy coupling of OpuA reconstituted in lipid nanodiscs. We show that anionic li...

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Bibliografiske detaljer
Main Authors: Karasawa, Akira, Swier, Lotteke J. Y. M., Stuart, Marc C. A., Brouwers, Jos, Helms, Bernd, Poolman, Bert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Membrane Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795284/
https://ncbi.nlm.nih.gov/pubmed/23979139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.499327
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