Cystathionine β-Synthase (CBS) Domains 1 and 2 Fulfill Different Roles in Ionic Strength Sensing of the ATP-binding Cassette (ABC) Transporter OpuA

The cystathionine β-synthase module of OpuA in conjunction with an anionic membrane surface acts as a sensor of internal ionic strength, which allows the protein to respond to osmotic stress. We now show by chemical modification and cross-linking studies that CBS2-CBS2 interface residues are critica...

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Hlavní autoři: Karasawa, Akira, Erkens, Guus B., Berntsson, Ronnie P.-A., Otten, Renee, Schuurman-Wolters, Gea K., Mulder, Frans A. A., Poolman, Bert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Membrane Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199475/
https://ncbi.nlm.nih.gov/pubmed/21878634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.284059
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