Anti-HER2 antibody and ScFvEGFR-conjugated antifouling magnetic iron oxide nanoparticles for targeting and magnetic resonance imaging of breast cancer

Antifouling magnetic iron oxide nanoparticles (IONPs) coated with block copolymer poly(ethylene oxide)-block-poly(γ-methacryloxypropyltrimethoxysilane) (PEO-b-PγMPS) were investigated for improving cell targeting by reducing nonspecific uptake. Conjugation of a HER2 antibody, Herceptin®, or a single...

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Detalhes bibliográficos
Main Authors: Chen, Hongwei, Wang, Liya, Yu, Qiqi, Qian, Weiping, Tiwari, Diana, Yi, Hong, Wang, Andrew Y, Huang, Jing, Yang, Lily, Mao, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794963/
https://ncbi.nlm.nih.gov/pubmed/24124366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S49069
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