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BCL-3 Attenuation of TNFA Expression Involves an Incoherent Feed-Forward Loop Regulated by Chromatin Structure

Induction of genes is rarely an isolated event; more typically occurring as part of a web of parallel interactions, or motifs, which act to refine and control gene expression. Here, we define an Incoherent Feed-forward Loop motif in which TNFα-induced NF-κB signalling activates expression of the TNF...

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Detalhes bibliográficos
Main Authors: Walker, Thomas, Adamson, Antony, Jackson, Dean A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794926/
https://ncbi.nlm.nih.gov/pubmed/24130828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077015
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