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Involvement of Calcium-Mediated Reactive Oxygen Species in Inductive GRP78 Expression by Geldanamycin in 9L Rat Brain Tumor Cells

Treatment with geldanamycin (GA) leads to an increase in [Ca(2+)](c) and the production of reactive oxygen species (ROS) in rat brain tumor 9L RBT cells. GA-exerted calcium signaling was blocked by BAPTA/AM and EGTA. The effect of GA on [Ca(2+)](c) was significantly reduced in the presence of thapsi...

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Autori principali: Sun, Fang-Chun, Shyu, Hsin-Yi, Lee, Meng-Shiou, Lee, Meng-Shiunn, Lai, Yiu-Kay
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794827/
https://ncbi.nlm.nih.gov/pubmed/24051401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140919169
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