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Minor Role of Mitochondrial Respiration for Fatty-Acid Induced Insulin Secretion

An appropriate insulin secretion by pancreatic beta-cells is necessary to maintain glucose homeostasis. A rise in plasma glucose leads to increased metabolism and an elevated cytoplasmic ATP/ADP ratio that finally triggers insulin granule exocytosis. In addition to this triggering pathway, one or mo...

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Detalhes bibliográficos
Main Authors: Schulz, Nadja, Kluth, Oliver, Jastroch, Martin, Schürmann, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794817/
https://ncbi.nlm.nih.gov/pubmed/24065099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140918989
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