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PPARδ is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction

The peroxisome proliferator-activated receptor δ (PPARδ) is implicated in regulation of mitochondrial processes in a number of tissues, and PPARδ activation is associated with decreased susceptibility to ectopic lipid deposition and metabolic disease. Here, we show that PPARδ is the PPAR subtype exp...

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Detalhes bibliográficos
Main Authors: Ravnskjaer, Kim, Frigerio, Francesca, Boergesen, Michael, Nielsen, Tina, Maechler, Pierre, Mandrup, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035500/
https://ncbi.nlm.nih.gov/pubmed/19965574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M001123
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