Lataa...

Assessing the Effect of Loop Mutations in the Folding Space of β(2)-Microglobulin with Molecular Dynamics Simulations

We use molecular dynamics simulations of a full atomistic Gō model to explore the impact of selected DE-loop mutations (D59P and W60C) on the folding space of protein human β(2)-microglobulin (Hβ(2)m), the causing agent of dialysis-related amyloidosis, a conformational disorder characterized by the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Estácio, Sílvia G., Shakhnovich, Eugene I., Faísca, Patrícia F. N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794727/
https://ncbi.nlm.nih.gov/pubmed/23975166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140917256
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!