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Universal digital high-resolution melt: a novel approach to broad-based profiling of heterogeneous biological samples

Comprehensive profiling of nucleic acids in genetically heterogeneous samples is important for clinical and basic research applications. Universal digital high-resolution melt (U-dHRM) is a new approach to broad-based PCR diagnostics and profiling technologies that can overcome issues of poor sensit...

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Bibliographic Details
Main Authors: Fraley, Stephanie I., Hardick, Justin, Jo Masek, Billie, Athamanolap, Pornpat, Rothman, Richard E., Gaydos, Charlotte A., Carroll, Karen C., Wakefield, Teresa, Wang, Tza-Huei, Yang, Samuel
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794612/
https://ncbi.nlm.nih.gov/pubmed/23935121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt684
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