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Early steps of active DNA demethylation initiated by ROS1 glycosylase require three putative helix-invading residues
Active DNA demethylation is crucial for epigenetic control, but the underlying enzymatic mechanisms are incompletely understood. REPRESSOR OF SILENCING 1 (ROS1) is a 5-methylcytosine (5-meC) DNA glycosylase/lyase that initiates DNA demethylation in plants through a base excision repair process. The...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3794587/ https://ncbi.nlm.nih.gov/pubmed/23868090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt625 |
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