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A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine

DNA cytosine methylation (5-meC) is a widespread epigenetic mark associated to gene silencing. In plants, DEMETER-LIKE (DML) proteins typified by Arabidopsis REPRESSOR OF SILENCING 1 (ROS1) initiate active DNA demethylation by catalyzing 5-meC excision. DML proteins belong to the HhH-GPD superfamily...

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Detalhes bibliográficos
Main Authors: Ponferrada-Marín, María Isabel, Parrilla-Doblas, Jara Teresa, Roldán-Arjona, Teresa, Ariza, Rafael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045615/
https://ncbi.nlm.nih.gov/pubmed/21036872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq982
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