Novel Biphasic Role of Resolvin D1 on Expression of Cyclooxygenase-2 in Lipopolysaccharide-Stimulated Lung Fibroblasts Is Partly through PI3K/AKT and ERK2 Pathways

Fibroblasts, far frombeing merely bystander cells, are known to play a specific role in inflammation resolution after an acute injury. As the endogenous “braking signal,” resolvins possess potent anti-inflammatory and proresolution actions. We demonstrated that the expression of COX-2 protein was si...

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Hlavní autoři: Wu, Derong, Zheng, Shengxing, Li, Wenjuan, Yang, Li, Liu, Yongjian, Zheng, Xia, Yang, Yi, Yang, Liangmin, Wang, Qian, Smith, Fang Gao, Jin, Shengwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794569/
https://ncbi.nlm.nih.gov/pubmed/24174713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/964012
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