Biphasic Regulation of Caveolin-1 Gene Expression by Fluoxetine in Astrocytes: Opposite Effects of PI3K/AKT and MAPK/ERK Signaling Pathways on c-fos

Previously, we reported that fluoxetine acts on 5-HT(2B) receptor and induces epidermal growth factor receptor (EGFR) transactivation in astrocytes. Recently, we have found that chronic treatment with fluoxetine regulates Caveolin-1 (Cav-1)/PTEN/PI3K/AKT/glycogen synthase kinase 3β (GSK-3β) signalin...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Li, Baoman, Jia, Shu, Yue, Tingting, Yang, Li, Huang, Chen, Verkhratsky, Alexej, Peng, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671492/
https://ncbi.nlm.nih.gov/pubmed/29163047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00335
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