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MARCH5 inactivation supports mitochondrial function during neurodegenerative stress

Neuronal cell death is accompanied by mitochondrial dysfunction with mitochondrial maintenance critical to neuronal survival. The mitochondrial ubiquitin ligase MARCH5 has dual roles in the upkeep of mitochondrial function. MARCH5 is involved in targeted degradation of proteins harmful to mitochondr...

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Detalhes bibliográficos
Main Authors: Fang, Lei, Li, Jia, Flammer, Josef, Neutzner, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794199/
https://ncbi.nlm.nih.gov/pubmed/24133412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00176
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