Thioredoxin Is Involved in Endothelial Cell Extracellular Transglutaminase 2 Activation Mediated by Celiac Disease Patient IgA

PURPOSE: To investigate the role of thioredoxin (TRX), a novel regulator of extracellular transglutaminase 2 (TG2), in celiac patients IgA (CD IgA) mediated TG2 enzymatic activation. METHODS: TG2 enzymatic activity was evaluated in endothelial cells (HUVECs) under different experimental conditions b...

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Hauptverfasser: Antonella Nadalutti, Cristina, Korponay-Szabo, Ilma Rita, Kaukinen, Katri, Wang, Zhuo, Griffin, Martin, Mäki, Markku, Lindfors, Katri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793942/
https://ncbi.nlm.nih.gov/pubmed/24130874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077277
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