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Oncolytic Adenovirus Retargeted to Delta-EGFR Induces Selective Antiglioma Activity

The fact that glioblastomas, which are one of the most devastating cancers, frequently express the Delta EGFR also called mutant variant III of EGFR (EGFRvIII) suggests that this cancer cell–specific receptor might serve as an ideal target for cancer therapy. To assess its potential as such a target...

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Autors principals: Piao, Y, Jiang, H, Alemany, R, Krasnykh, V, Marini, FC, Xu, J, Alonso, MM, Conrad, CA, Aldape, Kenneth D., Gomez-Manzano, C, Fueyo, J
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793894/
https://ncbi.nlm.nih.gov/pubmed/18927600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.75
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