Oncolytic Adenovirus Retargeted to Delta-EGFR Induces Selective Antiglioma Activity

The fact that glioblastomas, which are one of the most devastating cancers, frequently express the Delta EGFR also called mutant variant III of EGFR (EGFRvIII) suggests that this cancer cell–specific receptor might serve as an ideal target for cancer therapy. To assess its potential as such a target...

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Main Authors: Piao, Y, Jiang, H, Alemany, R, Krasnykh, V, Marini, FC, Xu, J, Alonso, MM, Conrad, CA, Aldape, Kenneth D., Gomez-Manzano, C, Fueyo, J
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793894/
https://ncbi.nlm.nih.gov/pubmed/18927600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.75
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