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Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages

The NLRP3 inflammasome is involved in many obesity-associated diseases, such as type 2 diabetes, atherosclerosis, and gouty arthritis, through its ability to induce interleukin (IL)-1β release. The molecular link between obesity and inflammasome activation is still unclear, but free fatty acids have...

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Detalhes bibliográficos
Main Authors: L'homme, Laurent, Esser, Nathalie, Riva, Laura, Scheen, André, Paquot, Nicolas, Piette, Jacques, Legrand-Poels, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793604/
https://ncbi.nlm.nih.gov/pubmed/24006511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M037861
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