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Bim, Bad, and Bax: a deadly combination in epileptic seizures
Several Bcl-2 family members, including Bim, may contribute to programmed cell death by inducing mitochondrial cytochrome c release, which activates caspase-9 and then caspase-3, the “executioner” of the cell. In this issue of the JCI, Shinoda and collaborators show the key role of Bim in epileptic...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC379331/ https://ncbi.nlm.nih.gov/pubmed/15057301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421478 |
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