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Bim, Bad, and Bax: a deadly combination in epileptic seizures

Several Bcl-2 family members, including Bim, may contribute to programmed cell death by inducing mitochondrial cytochrome c release, which activates caspase-9 and then caspase-3, the “executioner” of the cell. In this issue of the JCI, Shinoda and collaborators show the key role of Bim in epileptic...

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Detalhes bibliográficos
Main Authors: Niquet, Jerome, Wasterlain, Claude G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC379331/
https://ncbi.nlm.nih.gov/pubmed/15057301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421478
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