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Peripheral pre-positioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8(+) T cell responses in the lymph node
After an infection, the immune system generates long-lived memory lymphocytes whose increased frequency and altered state of differentiation enhance host defense against re-infection. Recently, the spatial distribution of memory cells was found to contribute to their protective function. Effector me...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793246/ https://ncbi.nlm.nih.gov/pubmed/23352234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.11.012 |
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